Role of Campylobacter jejuni Infection in the Pathogenesis of Guillain-Barré Syndrome: An Update
Joint Authors
Nyati, Kishan Kumar
Nyati, Roopanshi
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-13
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Our current knowledge on Campylobacter jejuni infections in humans has progressively increased over the past few decades.
Infection with C.
jejuni is the most common cause of bacterial gastroenteritis, sometimes surpassing other infections due to Salmonella, Shigella, and Escherichia coli.
Most infections are acquired due to consumption of raw or undercooked poultry, unpasteurized milk, and contaminated water.
After developing the diagnostic methods to detect C.
jejuni, the possibility to identify the association of its infection with new diseases has been increased.
After the successful isolation of C.
jejuni, reports have been published citing the occurrence of GBS following C.
jejuni infection.
Thus, C.
jejuni is now considered as a major triggering agent of GBS.
Molecular mimicry between sialylated lipooligosaccharide structures on the cell envelope of these bacteria and ganglioside epitopes on the human nerves that generates cross-reactive immune response results in autoimmune-driven nerve damage.
Though C.
jejuni is associated with several pathologic forms of GBS, axonal subtypes following C.
jejuni infection may be more severe.
Ample amount of existing data covers a large spectrum of GBS; however, the studies on C.
jejuni-associated GBS are still inconclusive.
Therefore, this review provides an update on the C.
jejuni infections engaged in the pathogenesis of GBS.
American Psychological Association (APA)
Nyati, Kishan Kumar& Nyati, Roopanshi. 2013. Role of Campylobacter jejuni Infection in the Pathogenesis of Guillain-Barré Syndrome: An Update. BioMed Research International،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-1005274
Modern Language Association (MLA)
Nyati, Kishan Kumar& Nyati, Roopanshi. Role of Campylobacter jejuni Infection in the Pathogenesis of Guillain-Barré Syndrome: An Update. BioMed Research International No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-1005274
American Medical Association (AMA)
Nyati, Kishan Kumar& Nyati, Roopanshi. Role of Campylobacter jejuni Infection in the Pathogenesis of Guillain-Barré Syndrome: An Update. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-1005274
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005274