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Ovarian Cancer Stem Cells: A New Target for Cancer Therapy
Joint Authors
Zhan, Qinglei
Wang, Chunmei
Ngai, Saiming
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Ovarian cancer is a highly lethal disease among all gynecologic malignancies and is the fifth leading cause of cancer-related death in women.
Although the standard combination of surgery and chemotherapy was initially effective in patients with ovarian cancer, disease relapse commonly occurred due to the generation of chemoresistance.
It has been reported that cancer stem cells (CSCs) are involved in drug resistance and cancer recurrence.
Over the past decades, increasing studies have been done to identify CSCs from human ovarian cancer cells.
The present paper will summarize different investigations on ovarian CSCs, including isolation, mechanisms of chemoresistance, and therapeutic approaches.
Although there are still numerous challenges to translate basic research to clinical applications, understanding the molecular details of CSCs is essential for developing effective strategies to prevent ovarian cancer and its recurrence.
American Psychological Association (APA)
Zhan, Qinglei& Wang, Chunmei& Ngai, Saiming. 2013. Ovarian Cancer Stem Cells: A New Target for Cancer Therapy. BioMed Research International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1005404
Modern Language Association (MLA)
Zhan, Qinglei…[et al.]. Ovarian Cancer Stem Cells: A New Target for Cancer Therapy. BioMed Research International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1005404
American Medical Association (AMA)
Zhan, Qinglei& Wang, Chunmei& Ngai, Saiming. Ovarian Cancer Stem Cells: A New Target for Cancer Therapy. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1005404
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005404