A Comprehensive Focus on Global Spectrum of BRCA1 and BRCA2 Mutations in Breast Cancer
Joint Authors
Karami, Fatemeh
Mehdipour, Parvin
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-21, 21 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-07
Country of Publication
Egypt
No. of Pages
21
Main Subjects
Abstract EN
Breast cancer (BC) is the most common cancer of women all over the world.
BRCA1 and BRCA2 gene mutations comprise the most important genetic susceptibility of BC.
Except for few common mutations, the spectrum of BRCA1 and BRCA2 mutations is heterogeneous in diverse populations.
185AGdel and 5382insC are the most important BRCA1 and BRCA2 alterations which have been encountered in most of the populations.
After those Ashkenazi founder mutations, 300T>G also demonstrated sparse frequency in African American and European populations.
This review affords quick access to the most frequent alterations among various populations which could be helpful in BRCA screening programs.
American Psychological Association (APA)
Karami, Fatemeh& Mehdipour, Parvin. 2013. A Comprehensive Focus on Global Spectrum of BRCA1 and BRCA2 Mutations in Breast Cancer. BioMed Research International،Vol. 2013, no. 2013, pp.1-21.
https://search.emarefa.net/detail/BIM-1005443
Modern Language Association (MLA)
Karami, Fatemeh& Mehdipour, Parvin. A Comprehensive Focus on Global Spectrum of BRCA1 and BRCA2 Mutations in Breast Cancer. BioMed Research International No. 2013 (2013), pp.1-21.
https://search.emarefa.net/detail/BIM-1005443
American Medical Association (AMA)
Karami, Fatemeh& Mehdipour, Parvin. A Comprehensive Focus on Global Spectrum of BRCA1 and BRCA2 Mutations in Breast Cancer. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-21.
https://search.emarefa.net/detail/BIM-1005443
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005443