Hypoglycemic and Hypolipidemic Potential of a High Fiber Diet in Healthy versus Diabetic Rabbits
Joint Authors
Díez, Raquel
García, Juan J.
Diez, M. José
Sierra, Matilde
Sahagún, Ana M.
Calle, Ángela P.
Fernández, Nélida
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The aim of this study was to investigate potential hypoglycaemic and hypolipidemic effects of Plantago ovata husk included in the diet, in healthy and diabetic rabbits.
We also examined the effects of this fiber in other biochemical parameters.
Two groups of 18 rabbits were used.
The first group was fed with standard chow and the second with chow supplemented with Plantago ovata husk (3.5 mg/kg/day).
On day 14 diabetes mellitus was induced by the intravenous administration of alloxan (80 mg/kg).
After an oral glucose load (3 g), glucose, insulin, and other biochemical parameters were determined on day 14 (healthy rabbits) and on day 28 (diabetic rabbits).
In healthy rabbits, fiber did not modify glucose or insulin levels but decreased significantly total cholesterol, LDL-cholesterol, atherogenic index, and glycosylated hemoglobin.
In diabetic rabbits, fiber was more beneficial in mild diabetics than in severe diabetics with significant decreases in glucose levels and increases in insulin concentrations.
In these animals fiber caused an important reduction in cholesterol, indicating a beneficial effect of Plantago ovata husk in diabetic rabbits.
Although further studies in patients are necessary, we think that Plantago ovata husk offers interesting perspectives to be administered to patients with diabetes mellitus.
American Psychological Association (APA)
Díez, Raquel& García, Juan J.& Diez, M. José& Sierra, Matilde& Sahagún, Ana M.& Calle, Ángela P.…[et al.]. 2013. Hypoglycemic and Hypolipidemic Potential of a High Fiber Diet in Healthy versus Diabetic Rabbits. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1005520
Modern Language Association (MLA)
Díez, Raquel…[et al.]. Hypoglycemic and Hypolipidemic Potential of a High Fiber Diet in Healthy versus Diabetic Rabbits. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1005520
American Medical Association (AMA)
Díez, Raquel& García, Juan J.& Diez, M. José& Sierra, Matilde& Sahagún, Ana M.& Calle, Ángela P.…[et al.]. Hypoglycemic and Hypolipidemic Potential of a High Fiber Diet in Healthy versus Diabetic Rabbits. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1005520
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005520