Perforating Disseminated Necrobiosis Lipoidica Diabeticorum

Abstract EN

Perforating necrobiosis lipoidica is a very rare clinical variant which consists of degeneration and transepidermal elimination of the collagen with few cases reported in the literature.

In two-thirds of the patients it associates with diabetes, with no relation with the glucose control.

We present a 42-year-old female patient with a 7-year history of diabetes on insulin therapy, referred to our clinic with a 3-year history of multiple asymptomatic firm plaques disseminated on the upper and lower extremities.

The clinical and histological findings proved the diagnosis of perforating necrobiosis lipoidica.