Autoimmune Hepatitis: Diagnostic Dilemma in the Setting of Suspected Iron Overload
Joint Authors
Ameda, Srujan
Laird-Fick, Heather S.
Tiwari, Ashish K.
An, In Chul
Source
Case Reports in Gastrointestinal Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-19
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Autoimmune hepatitis (AIH) is an inflammatory condition of the liver that has a multitude of clinical presentations from chronic hepatitis to acute fulminant hepatitis.
AIH diagnosis is typically suspected after ruling out other causes of hepatitis (such as vial hepatitis, hemochromatosis, Wilson’s disease, and primary biliary cirrhosis) through serological tests and by findings of high titers of certain autoantibodies (ANA and anti-SMA for type 1 AIH and anti-LKM-1 for type 2 AIH).
AIH like most inflammatory conditions is associated with increased ferritin levels (acute-phase reactant) but typically near-normal transferrin saturation.
The presence of excessive ferritin level in absence of high-transferrin saturation helps differentiate secondary iron overload from hemochromatosis where transferrin saturation is typically high.
We herein describe a case of AIH that presented with high ferritin levels and transferrin saturation suggesting a diagnosis of hemochromatosis and needed arduous work-up to arrive at accurate diagnosis of AIH.
American Psychological Association (APA)
An, In Chul& Tiwari, Ashish K.& Ameda, Srujan& Laird-Fick, Heather S.. 2013. Autoimmune Hepatitis: Diagnostic Dilemma in the Setting of Suspected Iron Overload. Case Reports in Gastrointestinal Medicine،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-1005718
Modern Language Association (MLA)
An, In Chul…[et al.]. Autoimmune Hepatitis: Diagnostic Dilemma in the Setting of Suspected Iron Overload. Case Reports in Gastrointestinal Medicine No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-1005718
American Medical Association (AMA)
An, In Chul& Tiwari, Ashish K.& Ameda, Srujan& Laird-Fick, Heather S.. Autoimmune Hepatitis: Diagnostic Dilemma in the Setting of Suspected Iron Overload. Case Reports in Gastrointestinal Medicine. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-1005718
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005718