![](/images/graphics-bg.png)
Clinical Use of Ultrasensitive Cardiac Troponin I Assay in Intermediate- and High-Risk Surgery Patients
Joint Authors
Borges, Flávia Kessler
Furtado, Mariana Vargas
Rossini, Ana Paula Webber
Bertoluci, Carolina
Gonzalez, Vinícius Leite
Bertoldi, Eduardo Gehling
Pezzali, Luíza Guazzeli
Machado, Daniel Luft
Grutcki, Denis Maltz
Rech, Leandro Gazziero
Magalhães, Mariana
Polanczyk, Carisi Anne
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Cardiac troponin levels have been reported to add value in the detection of cardiovascular complications in noncardiac surgery.
A sensitive cardiac troponin I (cTnI) assay could provide more accurate prognostic information.
Methods.
This study prospectively enrolled 142 patients with at least one Revised Cardiac Risk Index risk factor who underwent noncardiac surgery.
cTnI levels were measured postoperatively.
Short-term cardiac outcome predictors were evaluated.
Results.
cTnI elevation was observed in 47 patients, among whom 14 were diagnosed as having myocardial infarction (MI).
After 30 days, 16 patients had major adverse cardiac events (MACE).
Excluding patients with a final diagnosis of MI, predictors of cTnI elevation included dialysis, history of heart failure, transoperative major bleeding, and elevated levels of pre- and postoperative N-terminal pro-B-type natriuretic peptide (NT-proBNP).
Maximal cTnI values showed the highest sensitivity (94%), specificity (75%), and overall accuracy (AUC 0.89; 95% CI 0.80–0.98) for postoperative MACE.
Postoperative cTnI peak level (OR 9.4; 95% CI 2.3–39.2) and a preoperative NT-proBNP level ≥917 pg/mL (OR 3.47; 95% CI 1.05–11.6) were independent risk factors for MACE.
Conclusions.
cTnI was shown to be an independent prognostic factor for cardiac outcomes and should be considered as a component of perioperative risk assessment.
American Psychological Association (APA)
Borges, Flávia Kessler& Furtado, Mariana Vargas& Rossini, Ana Paula Webber& Bertoluci, Carolina& Gonzalez, Vinícius Leite& Bertoldi, Eduardo Gehling…[et al.]. 2013. Clinical Use of Ultrasensitive Cardiac Troponin I Assay in Intermediate- and High-Risk Surgery Patients. Disease Markers،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1005792
Modern Language Association (MLA)
Borges, Flávia Kessler…[et al.]. Clinical Use of Ultrasensitive Cardiac Troponin I Assay in Intermediate- and High-Risk Surgery Patients. Disease Markers No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1005792
American Medical Association (AMA)
Borges, Flávia Kessler& Furtado, Mariana Vargas& Rossini, Ana Paula Webber& Bertoluci, Carolina& Gonzalez, Vinícius Leite& Bertoldi, Eduardo Gehling…[et al.]. Clinical Use of Ultrasensitive Cardiac Troponin I Assay in Intermediate- and High-Risk Surgery Patients. Disease Markers. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1005792
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005792