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Cytokines Association with Clinical and Pathological Changes in Esophageal Squamous Cell Carcinoma
Author
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-17
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Carcinogenic transformation of cells in esophageal squamous cell carcinoma (ESCC) is characterized on molecular level by, among other things, changes in protein expression.
Among all proteins related to inflammation, cytokines may be implicated as possible biological markers of esophageal cancer.
These biomarkers, near imaging techniques, may be helpful in diagnosis and monitoring therapy in ESCC patients.
This review demonstrates findings of researches on dysregulation of cytokines in ESCC and their clinical and pathological implications.
Articles on cytokines were selected according to the following criteria: (i) the study was performed at protein level, (ii) the differences in cytokines expression or concentration were detected in tissues or serum from ESCC patients, (iii) the alterations of cytokines levels were detected by: immunohistochemistry (IHC), western blot (WB) and enzyme-linked immunosorbent assay (ELISA).
Members of VEGF family seem to play an essential role as potential markers in ESCC.
The results of all cytokines researches are promising but further studies are necessary to establish the biological significance of these peptydes in ESCC, their potential usefulness for early diagnosis, pre- and postoperative prognosis and monitoring of the respond to chemo- and radiotherapy of cancer patients.
American Psychological Association (APA)
Diakowska, Dorota. 2013. Cytokines Association with Clinical and Pathological Changes in Esophageal Squamous Cell Carcinoma. Disease Markers،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1005812
Modern Language Association (MLA)
Diakowska, Dorota. Cytokines Association with Clinical and Pathological Changes in Esophageal Squamous Cell Carcinoma. Disease Markers No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-1005812
American Medical Association (AMA)
Diakowska, Dorota. Cytokines Association with Clinical and Pathological Changes in Esophageal Squamous Cell Carcinoma. Disease Markers. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1005812
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005812