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Rheumatoid Factors: Clinical Applications
Joint Authors
Ingegnoli, Francesca
Castelli, Roberto
Gualtierotti, Roberta
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-13
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Rheumatoid factors are antibodies directed against the Fc region of immunoglobulin G.
First detected in patients with rheumatoid arthritis 70 years ago, they can also be found in patients with other autoimmune and nonautoimmune conditions, as well as in healthy subjects.
Rheumatoid factors form part of the workup for the differential diagnosis of arthropathies.
In clinical practice, it is recommended to measure anti-cyclic citrullinated peptide antibodies and rheumatoid factors together because anti-cyclic citrullinated peptide antibodies alone are only moderately sensitive, and the combination of the two markers improves diagnostic accuracy, especially in the case of early rheumatoid arthritis.
Furthermore, different rheumatoid factor isotypes alone or in combination can be helpful when managing rheumatoid arthritis patients, from the time of diagnosis until deciding on the choice of therapeutic strategy.
American Psychological Association (APA)
Ingegnoli, Francesca& Castelli, Roberto& Gualtierotti, Roberta. 2013. Rheumatoid Factors: Clinical Applications. Disease Markers،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1005862
Modern Language Association (MLA)
Ingegnoli, Francesca…[et al.]. Rheumatoid Factors: Clinical Applications. Disease Markers No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1005862
American Medical Association (AMA)
Ingegnoli, Francesca& Castelli, Roberto& Gualtierotti, Roberta. Rheumatoid Factors: Clinical Applications. Disease Markers. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1005862
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005862