Experimental and Clinical Pharmacology of Andrographis paniculata and Its Major Bioactive Phytoconstituent Andrographolide
Joint Authors
Hsieh, Cheng-Ying
Lee, Jie-Jen
Sheu, Joen-Rong
Jayakumar, Thanasekaran
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-24
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Andrographis paniculata (Burm.
F) Nees, generally known as “king of bitters,” is an herbaceous plant in the family Acanthaceae.
In China, India, Thailand, and Malaysia, this plant has been widely used for treating sore throat, flu, and upper respiratory tract infections.
Andrographolide, a major bioactive chemical constituent of the plant, has shown anticancer potential in various investigations.
Andrographolide and its derivatives have anti-inflammatory effects in experimental models asthma, stroke, and arthritis.
In recent years, pharmaceutical chemists have synthesized numerous andrographolide derivatives, which exhibit essential pharmacological activities such as those that are anti-inflammatory, antibacterial, antitumor, antidiabetic, anti-HIV, antifeedant, and antiviral.
However, what is noteworthy about this paper is summarizing the effects of andrographolide against cardiovascular disease, platelet activation, infertility, and NF-κB activation.
Therefore, this paper is intended to provide evidence reported in relevant literature on qualitative research to assist scientists in isolating and characterizing bioactive compounds.
American Psychological Association (APA)
Jayakumar, Thanasekaran& Hsieh, Cheng-Ying& Lee, Jie-Jen& Sheu, Joen-Rong. 2013. Experimental and Clinical Pharmacology of Andrographis paniculata and Its Major Bioactive Phytoconstituent Andrographolide. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-1005907
Modern Language Association (MLA)
Jayakumar, Thanasekaran…[et al.]. Experimental and Clinical Pharmacology of Andrographis paniculata and Its Major Bioactive Phytoconstituent Andrographolide. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-16.
https://search.emarefa.net/detail/BIM-1005907
American Medical Association (AMA)
Jayakumar, Thanasekaran& Hsieh, Cheng-Ying& Lee, Jie-Jen& Sheu, Joen-Rong. Experimental and Clinical Pharmacology of Andrographis paniculata and Its Major Bioactive Phytoconstituent Andrographolide. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-1005907
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005907