Physiological effects of lactic acid bacteria against melamine induced toxicity in female albino rats

Abstract EN

The aim of this study was to investigate the ameliorative effect of two type of lactic acid bacteria Lactobacillus casei and Lactobacillus acidophilus against melamine toxicity by some physiological indicators in mature female rats after 21 days.

In this study using 35 of female mature rats and divided randomly into seven groups each group contain five animals.

The results showed that melamine caused a significant decrease in the organs weights liver and spleen and increase in kidney weight with increase of melamine concentration.

Also showed to decrease in value of hemoglobin, red blood cells, white blood cells, lymphocyte and platelets, while the values of granules were increasing with increase of melamine concentration as compared with control group.

Also found that the addition of melamine led to increase in cholesterol, low density lipoproteins and blood glucose, while the values of triglyceride and high density lipoproteins was decreased with increase of melamine concentration.

The addition of two types of lactic acid bacteria L.

casei and L.

acidophilus led to decreasing the negative effect of melamine on the values of all the parameters determined.