Antimicrobial activity of peptides extracted from camels' blood neutrophils against some pathogenic bacteria

Abstract EN

The aim of the current research was to isolate and purify antimicrobial cationic peptides (Amps) taken from camel blood and to study its antibacterial activity against some multidrug-resistant pathogenic bacteria Salmonella typhimurium, Bacillus subtilis.

The results showed the possibility of obtaining these peptides from camel's white blood cells, and was separated by using Reversed-Phased-High Performance Liquid Chromatography (RP-HPLC) technical equipment.

The results showed the presence of 21 absorption peaks of the isolated peptide extract.

The two-stage-radial diffusions method was used to study the activity of the crude peptide against the studied bacteria.

The results showed that these peptides were effective without any resistance.

The best effect was on the Bacillus subtilis with a diameter of 31 mm inhibition, while the less effect was on the Salmonella typhimurium with a diameter of 20 mm