The Controversial Role of Microglia in Malignant Gliomas
Joint Authors
Wei, Jun
Gabrusiewicz, Konrad
Heimberger, Amy
Source
Journal of Immunology Research
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-24
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Malignant gliomas contain stroma and a variety of immune cells including abundant activated microglia/macrophages.
Mounting evidence indicates that the glioma microenvironment converts the glioma-associated microglia/macrophages (GAMs) into glioma-supportive, immunosuppressive cells; however, GAMs can retain intrinsic anti-tumor properties.
Here, we review and discuss this duality and the potential therapeutic strategies that may inhibit their glioma-supportive and propagating functions.
American Psychological Association (APA)
Wei, Jun& Gabrusiewicz, Konrad& Heimberger, Amy. 2013. The Controversial Role of Microglia in Malignant Gliomas. Journal of Immunology Research،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-1006587
Modern Language Association (MLA)
Wei, Jun…[et al.]. The Controversial Role of Microglia in Malignant Gliomas. Journal of Immunology Research No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-1006587
American Medical Association (AMA)
Wei, Jun& Gabrusiewicz, Konrad& Heimberger, Amy. The Controversial Role of Microglia in Malignant Gliomas. Journal of Immunology Research. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-1006587
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1006587
