Chemokines in Chronic Liver Allograft Dysfunction Pathogenesis and Potential Therapeutic Targets
Joint Authors
Source
Journal of Immunology Research
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-08
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Despite advances in immunosuppressive drugs, long-term success of liver transplantation is still limited by the development of chronic liver allograft dysfunction.
Although the exact pathogenesis of chronic liver allograft dysfunction remains to be established, there is strong evidence that chemokines are involved in organ damage induced by inflammatory and immune responses after liver surgery.
Chemokines are a group of low-molecular-weight molecules whose function includes angiogenesis, haematopoiesis, mitogenesis, organ fibrogenesis, tumour growth and metastasis, and participating in the development of the immune system and in inflammatory and immune responses.
The purpose of this review is to collect all the research that has been done so far concerning chemokines and the pathogenesis of chronic liver allograft dysfunction and helpfully, to pave the way for designing therapeutic strategies and pharmaceutical agents to ameliorate chronic allograft dysfunction after liver transplantation.
American Psychological Association (APA)
Liu, Bin& Li, Jing& Yan, Lu-Nan. 2013. Chemokines in Chronic Liver Allograft Dysfunction Pathogenesis and Potential Therapeutic Targets. Journal of Immunology Research،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-1006602
Modern Language Association (MLA)
Liu, Bin…[et al.]. Chemokines in Chronic Liver Allograft Dysfunction Pathogenesis and Potential Therapeutic Targets. Journal of Immunology Research No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-1006602
American Medical Association (AMA)
Liu, Bin& Li, Jing& Yan, Lu-Nan. Chemokines in Chronic Liver Allograft Dysfunction Pathogenesis and Potential Therapeutic Targets. Journal of Immunology Research. 2013. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-1006602
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1006602