Mesoporous Silicon Microparticles Enhance MHC Class I Cross-Antigen Presentation by Human Dendritic Cells
Joint Authors
Diez-Rivero, C. M.
Matveyeva, E.
Martínez-Naves, E.
Reche, P. A.
López Relaño, J.
Abos Gracia, B.
Gómez del Moral, M.
Jiménez-Periáñez, A.
Source
Journal of Immunology Research
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The mesoporous silicon microparticles (MSMPs) are excellent vehicles for releasing molecules inside the cell.
The aim of this work was to use MSMPs to deliver viral specific MHC class I restricted epitopes into human antigen presenting cells (monocyte derived dendritic cells, MDDCs) to facilitate their capture, processing, and presentation to CD8+ (cytotoxic) T lymphocytes.
We show for the first time that MSMPs vehiculation of antigenic peptides enhances their MHC class I presentation by human MDDCs to CD8 T lymphocytes.
American Psychological Association (APA)
Jiménez-Periáñez, A.& Abos Gracia, B.& López Relaño, J.& Diez-Rivero, C. M.& Reche, P. A.& Martínez-Naves, E.…[et al.]. 2013. Mesoporous Silicon Microparticles Enhance MHC Class I Cross-Antigen Presentation by Human Dendritic Cells. Journal of Immunology Research،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1006648
Modern Language Association (MLA)
Jiménez-Periáñez, A.…[et al.]. Mesoporous Silicon Microparticles Enhance MHC Class I Cross-Antigen Presentation by Human Dendritic Cells. Journal of Immunology Research No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1006648
American Medical Association (AMA)
Jiménez-Periáñez, A.& Abos Gracia, B.& López Relaño, J.& Diez-Rivero, C. M.& Reche, P. A.& Martínez-Naves, E.…[et al.]. Mesoporous Silicon Microparticles Enhance MHC Class I Cross-Antigen Presentation by Human Dendritic Cells. Journal of Immunology Research. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1006648
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1006648