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Late and Chronic Antibody-Mediated Rejection: Main Barrier to Long Term Graft Survival
Joint Authors
Source
Journal of Immunology Research
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Antibody-mediated rejection (AMR) is an important cause of graft loss after organ transplantation.
It is caused by anti-donor-specific antibodies especially anti-HLA antibodies.
C4d had been regarded as a diagnosis marker for AMR.
Although most early AMR episodes can be successfully controlled or reversed, late and chronic AMR remains the leading cause of late graft loss.
The strategies which work in early AMR have limited effect on late/chronic episodes.
Here, we reviewed the lines of evidence that late/chronic AMR is the leading cause of late graft loss, characteristics of late AMR, and current strategies in managing late/chronic AMR.
More effort should be put on the management of late/chronic AMR to make a better long term graft survival.
American Psychological Association (APA)
Sun, Qiquan& Yang, Yang. 2013. Late and Chronic Antibody-Mediated Rejection: Main Barrier to Long Term Graft Survival. Journal of Immunology Research،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1006977
Modern Language Association (MLA)
Sun, Qiquan& Yang, Yang. Late and Chronic Antibody-Mediated Rejection: Main Barrier to Long Term Graft Survival. Journal of Immunology Research No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1006977
American Medical Association (AMA)
Sun, Qiquan& Yang, Yang. Late and Chronic Antibody-Mediated Rejection: Main Barrier to Long Term Graft Survival. Journal of Immunology Research. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1006977
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1006977