Mitochondrial Quality Control: Decommissioning Power Plants in Neurodegenerative Diseases
Joint Authors
Mukherjee, Rukmini
Chakrabarti, Oishee
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-28
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
The cell has an intricate quality control system to protect its mitochondria from oxidative stress.
This surveillance system is multi-tiered and comprises molecules that are present inside the mitochondria, in the cytosol, and in other organelles like the nucleus and endoplasmic reticulum.
These molecules cross talk with each other and protect the mitochondria from oxidative stress.
Oxidative stress is a fundamental part of early disease pathogenesis of neurodegenerative diseases.
These disorders also damage the cellular quality control machinery that protects the cell against oxidative stress.
This exacerbates the oxidative damage and causes extensive neuronal cell death that is characteristic of neurodegeneration.
American Psychological Association (APA)
Mukherjee, Rukmini& Chakrabarti, Oishee. 2013. Mitochondrial Quality Control: Decommissioning Power Plants in Neurodegenerative Diseases. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1011618
Modern Language Association (MLA)
Mukherjee, Rukmini& Chakrabarti, Oishee. Mitochondrial Quality Control: Decommissioning Power Plants in Neurodegenerative Diseases. The Scientific World Journal No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-1011618
American Medical Association (AMA)
Mukherjee, Rukmini& Chakrabarti, Oishee. Mitochondrial Quality Control: Decommissioning Power Plants in Neurodegenerative Diseases. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1011618
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1011618