Laboratory Diagnosis of Human Rabies: Recent Advances
Joint Authors
Mani, Reeta Subramaniam
Madhusudana, Shampur Narayan
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-14
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Rabies, an acute progressive, fatal encephalomyelitis, transmitted most commonly through the bite of a rabid animal, is responsible for an estimated 61,000 human deaths worldwide.
The true disease burden and public health impact due to rabies remain underestimated due to lack of sensitive laboratory diagnostic methods.
Rapid diagnosis of rabies can help initiate prompt infection control and public health measures, obviate the need for unnecessary treatment/medical tests, and assist in timely administration of pre- or postexposure prophylactic vaccination to family members and medical staff.
Antemortem diagnosis of human rabies provides an impetus for clinicians to attempt experimental therapeutic approaches in some patients, especially after the reported survival of a few cases of human rabies.
Traditional methods for antemortem and postmortem rabies diagnosis have several limitations.
Recent advances in technology have led to the improvement or development of several diagnostic assays which include methods for rabies viral antigen and antibody detection and assays for viral nucleic acid detection and identification of specific biomarkers.
These assays which complement traditional methods have the potential to revolutionize rabies diagnosis in future.
American Psychological Association (APA)
Mani, Reeta Subramaniam& Madhusudana, Shampur Narayan. 2013. Laboratory Diagnosis of Human Rabies: Recent Advances. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1012531
Modern Language Association (MLA)
Mani, Reeta Subramaniam& Madhusudana, Shampur Narayan. Laboratory Diagnosis of Human Rabies: Recent Advances. The Scientific World Journal No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1012531
American Medical Association (AMA)
Mani, Reeta Subramaniam& Madhusudana, Shampur Narayan. Laboratory Diagnosis of Human Rabies: Recent Advances. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1012531
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1012531