Investigation of the Presence of Biofilms in Chronic Suppurative Otitis Media, Nonsuppurative Otitis Media, and Chronic Otitis Media with Cholesteatoma by Scanning Electron Microscopy
Joint Authors
Kaya, Ercan
Dag, Ilknur
Incesulu, Armagan
Gurbuz, Melek Kezban
Acar, Mustafa
Birdane, Leman
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-27
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Biofilms have been shown to play a major role in the pathogenesis of otolaryngologic infections.
However, very limited studies have been undertaken to demonstrate the presence of biofilms in tissues from patients with chronic otitis media (COM) with or without cholesteatoma.
Our objective is to study the presence of biofilms in humans with chronic suppurative and nonsuppurative otitis media and cholesteatoma.
Study Design.
In all, 102 tissue specimens (middle ear, mastoid tissue, and ossicle samples) were collected during surgery from 34 patients.
Methods.
The samples were processed for the investigation of biofilms by scanning electron microscopy (SEM).
Results.
Our research supports the hypothesis in which biofilms are involved in chronic suppurative otitis media, cholesteatoma, and, to a lesser degree, chronic nonsuppurative otitis media.
There were higher rates in hypertrophic and granulated tissue samples than in normal mucosa.
In addition, the presence of biofilms was significantly higher in the middle ear mucosa compared with the mastoid and ossicle samples.
Conclusion.
In the clinic, the careful use of topical or systemic antimicrobials is essential, and, during surgery, hypertrophic tissue must be carefully removed from normal tissue.
American Psychological Association (APA)
Kaya, Ercan& Dag, Ilknur& Incesulu, Armagan& Gurbuz, Melek Kezban& Acar, Mustafa& Birdane, Leman. 2013. Investigation of the Presence of Biofilms in Chronic Suppurative Otitis Media, Nonsuppurative Otitis Media, and Chronic Otitis Media with Cholesteatoma by Scanning Electron Microscopy. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1012662
Modern Language Association (MLA)
Kaya, Ercan…[et al.]. Investigation of the Presence of Biofilms in Chronic Suppurative Otitis Media, Nonsuppurative Otitis Media, and Chronic Otitis Media with Cholesteatoma by Scanning Electron Microscopy. The Scientific World Journal No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1012662
American Medical Association (AMA)
Kaya, Ercan& Dag, Ilknur& Incesulu, Armagan& Gurbuz, Melek Kezban& Acar, Mustafa& Birdane, Leman. Investigation of the Presence of Biofilms in Chronic Suppurative Otitis Media, Nonsuppurative Otitis Media, and Chronic Otitis Media with Cholesteatoma by Scanning Electron Microscopy. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1012662
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1012662