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Maternal Hypotension during Fetoscopic Surgery: Incidence and Its Impact on Fetal Survival Outcomes
Joint Authors
Ngamprasertwong, Pornswan
Habli, Mounira
Boat, Anne
Lim, Foong Yen
Esslinger, Hope
Ding, Lili
Sadhasivam, Senthilkumar
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
In this retrospective cohort study, we aimed to determine the incidence of intraoperative maternal hypotension during fetoscopic surgery for twin-twin transfusion syndrome (TTTS) and to evaluate the impact of intraoperative hypotension on fetal survival.
A total of 328 TTTS patients with recipient twin cardiomyopathy who underwent fetoscopic surgery under epidural anesthesia were included.
The exposure of interest was maternal medical therapy with nifedipine for the treatment of fetal cardiomyopathy.
We found that intraoperative hypotension occurred in 53.4% (175/328 patients).
There was no statistically significant difference in incidence of hypotension between nifedipine exposure and nonexposure groups (54.8% versus 50.8%, P=0.479).
However, the nifedipine exposure group received a statistically significant higher dose of phenylephrine (7.04 ± 6.38 mcg/kg versus 4.70 ± 4.14 mcg/kg, P=0.018) and higher doses of other vasopressor, as counted by number of treatments (6.06 ± 4.58 versus 4.96 ± 3.42, P=0.022).
There were no statistically significant differences in acute fetal survival rate (within 5 days) and fetal survival rate at birth between hypotensive and nonhypotensive patients.
We concluded that preoperative exposure to nifedipine resulted in increased intraoperative maternal vasopressor requirement during fetoscopic surgery under epidural anesthesia.
In patients who had intraoperative maternal hypotension, there was no correlation between the presence of maternal hypotension and postoperative fetal survival.
American Psychological Association (APA)
Ngamprasertwong, Pornswan& Habli, Mounira& Boat, Anne& Lim, Foong Yen& Esslinger, Hope& Ding, Lili…[et al.]. 2013. Maternal Hypotension during Fetoscopic Surgery: Incidence and Its Impact on Fetal Survival Outcomes. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1012761
Modern Language Association (MLA)
Ngamprasertwong, Pornswan…[et al.]. Maternal Hypotension during Fetoscopic Surgery: Incidence and Its Impact on Fetal Survival Outcomes. The Scientific World Journal No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1012761
American Medical Association (AMA)
Ngamprasertwong, Pornswan& Habli, Mounira& Boat, Anne& Lim, Foong Yen& Esslinger, Hope& Ding, Lili…[et al.]. Maternal Hypotension during Fetoscopic Surgery: Incidence and Its Impact on Fetal Survival Outcomes. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1012761
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1012761