Computational and Bioinformatics Frameworks for Next-Generation Whole Exome and Genome Sequencing
Joint Authors
Dolled-Filhart, Marisa P.
Lee, Michael
Ou-yang, Chih-wen
Haraksingh, Rajini Rani
Lin, Jimmy Cheng-Ho
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-13
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
It has become increasingly apparent that one of the major hurdles in the genomic age will be the bioinformatics challenges of next-generation sequencing.
We provide an overview of a general framework of bioinformatics analysis.
For each of the three stages of (1) alignment, (2) variant calling, and (3) filtering and annotation, we describe the analysis required and survey the different software packages that are used.
Furthermore, we discuss possible future developments as data sources grow and highlight opportunities for new bioinformatics tools to be developed.
American Psychological Association (APA)
Dolled-Filhart, Marisa P.& Lee, Michael& Ou-yang, Chih-wen& Haraksingh, Rajini Rani& Lin, Jimmy Cheng-Ho. 2013. Computational and Bioinformatics Frameworks for Next-Generation Whole Exome and Genome Sequencing. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1012806
Modern Language Association (MLA)
Dolled-Filhart, Marisa P.…[et al.]. Computational and Bioinformatics Frameworks for Next-Generation Whole Exome and Genome Sequencing. The Scientific World Journal No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1012806
American Medical Association (AMA)
Dolled-Filhart, Marisa P.& Lee, Michael& Ou-yang, Chih-wen& Haraksingh, Rajini Rani& Lin, Jimmy Cheng-Ho. Computational and Bioinformatics Frameworks for Next-Generation Whole Exome and Genome Sequencing. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1012806
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1012806