Connection and Deformation of Pathological Images via a Macro Image for Comparing Different Modality Images of Brain Tumor

Abstract EN

Magnetic resonance imaging (MRI) is a preferred modality for diagnosis of brain tumor.

However, because infiltrated regions with tumor are often indistinct on the MR image, it is difficult to identify tumor regions exactly.

For revealing the relationship between tissue information and MR signal of the tumor, pathological images and MR images at the same regions have to be analyzed.

However, it is not easy to make relationship between pathological images and MR images because pathological images are divided and deformed through tissue specimen making.

We propose a registration scheme of a set of pathological images and MR image by referring a macro image captured by an optical camera.

In the first step, parted pathological images are pieced together and deformed with macro image.

In the second step, connected pathological image is registered to MR image.

This paper shows connection and deformation methods for the pathological image.