Determining Risk Factors of Bleeding in Patients on Warfarin Treatment
Joint Authors
Uygungül, Evren
Ayrik, Cuneyt
Narci, Huseyin
Erdoğan, Semra
Toker, İbrahim
Demir, Filiz
Karaaslan, Ulas
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-09
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Warfarin is a commonly used oral anticoagulant agent.
The most common adverse effects of warfarin are bleeding complications.
Methods.
We performed a 1-year retrospective chart review of emergency department patients using warfarin.
A total of 65 patients with bleeding disorder (study group) and 63 patients without bleeding (control group) were included, making up a total of 128 subjects.
Demographic data, frequency of international normalized ratio (INR) checks, and routine blood results were extracted.
Logistic regression analysis was used to determine which factors were most closely associated with bleeding complications.
Results.
Median age was 62.0 ± 14.4 and 61.9 ± 14.5 for study group and control group, respectively.
Educational status and frequency of INR checks were similar in both groups ( P = 0.101 and P = 0.483 , resp.).
INR levels were higher in the study group ( 5.45 ± 3.98 versus 2.63 ± 1.71 , P < 0.001 ).
Creatinine levels were also higher in the study group ( 1.14 ± 0.57 mg/dL versus 0.94 ± 0.38 mg/dL, P = 0.042 ).
Acetylsalicylic acid use was more frequent in the study group and was associated with a 9-fold increase in bleeding complications ( P < 0.001 ) .
Conclusions.
High INR levels, high creatinine levels, and acetylsalicylic acid use were associated with bleeding complications in ED patients using warfarin.
American Psychological Association (APA)
Uygungül, Evren& Ayrik, Cuneyt& Narci, Huseyin& Erdoğan, Semra& Toker, İbrahim& Demir, Filiz…[et al.]. 2014. Determining Risk Factors of Bleeding in Patients on Warfarin Treatment. Advances in Hematology،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1015337
Modern Language Association (MLA)
Uygungül, Evren…[et al.]. Determining Risk Factors of Bleeding in Patients on Warfarin Treatment. Advances in Hematology No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1015337
American Medical Association (AMA)
Uygungül, Evren& Ayrik, Cuneyt& Narci, Huseyin& Erdoğan, Semra& Toker, İbrahim& Demir, Filiz…[et al.]. Determining Risk Factors of Bleeding in Patients on Warfarin Treatment. Advances in Hematology. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1015337
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1015337