Assessment of Size-Dependent Antimicrobial and Cytotoxic Properties of Silver Nanoparticles
Joint Authors
Jeong, Yoon
Lim, Dong Woo
Choi, Jonghoon
Source
Advances in Materials Science and Engineering
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-14
Country of Publication
Egypt
No. of Pages
6
Abstract EN
Nanoscale silver has been increasingly applied to commercial products for their antimicrobial function as antibiotics and disinfectants.
In this work, the different sizes of silver nanoparticles (AgNPs) were studied not only in Methylobacterium spp.
for their antimicrobial potential but also in human peripheral blood mononuclear cells (PBMCs) for their cytotoxicity in order to determine responses dependent on their particle size.
Size controlled silver particles were prepared by chemical reduction of silver cations (Ag+) and then dispersed in water for their physicochemical characterization using transmission electron microscopy (TEM), dynamic light scattering (DLS), and zeta potential measurements.
To ascertain antimicrobial response, water-soluble silver nanoparticles were mixed into Methylobacterium spp.
cultured for two days and the sample from the broth was spread on the agar plate for colony counting.
10 nm nanoparticles showed more antimicrobial activity than 100 nm particles at which concentrations were equivalently controlled.
Increased cytotoxic effect of smaller silver nanoparticles was also observed in PBMCs cocultured with particles.
Silver ions released from 10 nm particles might be correlated with upregulated antimicrobial and cytotoxic properties of AgNPs.
American Psychological Association (APA)
Jeong, Yoon& Lim, Dong Woo& Choi, Jonghoon. 2014. Assessment of Size-Dependent Antimicrobial and Cytotoxic Properties of Silver Nanoparticles. Advances in Materials Science and Engineering،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1015857
Modern Language Association (MLA)
Jeong, Yoon…[et al.]. Assessment of Size-Dependent Antimicrobial and Cytotoxic Properties of Silver Nanoparticles. Advances in Materials Science and Engineering No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1015857
American Medical Association (AMA)
Jeong, Yoon& Lim, Dong Woo& Choi, Jonghoon. Assessment of Size-Dependent Antimicrobial and Cytotoxic Properties of Silver Nanoparticles. Advances in Materials Science and Engineering. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1015857
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1015857