HBV and HCV Coinfection among HIVAIDS Patients in the National Hospital of Tropical Diseases, Vietnam

Abstract EN

Aim.

To examine prevalence and characterization of HBV and HCV coinfection among HIV/AIDS patients.

Methods.

This cross-sectional, retrospective study analyzed 724 HIV/AIDS patients in the HIV clinic at the National Hospital of Tropical Diseases (NHTD), from 5/2005 to 4/2011.

Results.

The prevalence of HBV, HCV, and HIV coinfection was 50.3% (364/724), of which HbsAg, HCV, and both of HbsAg, and HCV positivity were 8.4%, 35.4%, and 6.5%, respectively.

The cohort (364 patients) with HBV, HCV, and HIV coinfection live in the 30 provinces/cities in the North and Central area of Vietnam.

We found statistically significant associations between heightened risk of coinfection with HIV and HCV in the age group 30–39 years ( P < 0.001 ), male gender ( P < 0.001 ), never married patients ( P < 0.001 ), patients with a history of injection drug use ( P < 0.001 ), and clinical stages 2–4 ( P < 0.001 ).

Coinfection with HBV/HIV was statistically significant associations between heightened risk of marital status (never married) ( P < 0.001 ) and those who reported transmission through sexual intercourse.

Conclusion.

Coinfection with viral hepatitis is common in HIV patients; further study of the impact and evolution of coinfection is necessary to find effective treatment algorithms.