Synthesis and Characterisation of Copper(II) Complexes with Tridentate NNO Functionalized Ligand: Density Function Theory Study, DNA Binding Mechanism, Optical Properties, and Biological Application
Joint Authors
Hazra, Madhumita
Dolai, Tanushree
Pandey, Akhil
Dey, Subrata Kumar
Patra, Animesh
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-16
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
The photo physical properties of two mononuclear pentacoordinated copper(II) complexes formulated as [Cu(L)(Cl)(H2O)] (1) and [Cu(L)(Br)(H2O)] (2) HL = (1-[(3-methyl-pyridine-2-ylimino)-methyl]-naphthalen-2-ol) were synthesized and characterized by elemental, physicochemical, and spectroscopic methods.
The density function theory calculations are used to investigate the electronic structures and the electronic properties of ligand and complex.
The interactions of copper(II) complexes towards calf thymus DNA were examined with the help of absorption, viscosity, and fluorescence spectroscopic techniques at pH 7.40.
All spectroscopy's result indicates that complexes show good binding activity to calf thymus DNA through groove binding.
The optical absorption and fluorescence emission properties of microwires were characterized by fluorescence microscope.
From a spectroscopic viewpoint, all compounds strongly emit green light in the solid state.
The microscopy investigation suggested that microwires exhibited optical waveguide behaviour which are applicable as fluorescent nanomaterials and can be used as building blocks for miniaturized photonic devices.
Antibacterial study reveals that complexes are better antimicrobial agents than free Schiff base due to bacterial cell penetration by chelation.
Moreover, the antioxidant study of the ligand and complexes is evaluated by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free-radical assays, which demonstrate that the complexes are of higher antioxidant activity than free ligand.
American Psychological Association (APA)
Hazra, Madhumita& Dolai, Tanushree& Pandey, Akhil& Dey, Subrata Kumar& Patra, Animesh. 2014. Synthesis and Characterisation of Copper(II) Complexes with Tridentate NNO Functionalized Ligand: Density Function Theory Study, DNA Binding Mechanism, Optical Properties, and Biological Application. Bioinorganic Chemistry and Applications،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1016066
Modern Language Association (MLA)
Hazra, Madhumita…[et al.]. Synthesis and Characterisation of Copper(II) Complexes with Tridentate NNO Functionalized Ligand: Density Function Theory Study, DNA Binding Mechanism, Optical Properties, and Biological Application. Bioinorganic Chemistry and Applications No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-1016066
American Medical Association (AMA)
Hazra, Madhumita& Dolai, Tanushree& Pandey, Akhil& Dey, Subrata Kumar& Patra, Animesh. Synthesis and Characterisation of Copper(II) Complexes with Tridentate NNO Functionalized Ligand: Density Function Theory Study, DNA Binding Mechanism, Optical Properties, and Biological Application. Bioinorganic Chemistry and Applications. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1016066
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016066