Synthesis, Structural Characterization, and Evaluation of the Biological Properties of Heteroleptic Palladium(II) Complexes
Joint Authors
Khan, Hizbullah
Daraz, Nek
Khan, Muhammad Nasim
Said, Muhammad
Akhtar, Nosheen
Badshah, Amin
Khan, Amir Sada
Ali, Murad
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Five heteroleptic palladium(II) complexes of the general formula Pd(PR3)(tu)Cl2, where PR3 = triphenylphosphine (1), diphenyl-o-tolylphosphine (2), diphenyl-p-tolylphosphine (3), diphenyl-t-butylphosphine (4), and diphenyl-o-methoxyphenylphosphine (5), and tu = 1,3-bis(2-methoxyphenyl) thiourea.
They all have been synthesized and characterized by various spectroscopic techniques (elemental analysis, FTIR, and 1H NMR and the ligand 1,3-bis(2-methoxyphenyl) thiourea was synthesized by single crystal X-ray diffraction technique).
The synthesized compounds were screened for their antibacterial activity against four strains of bacteria (Escherichia coli, Shigella flexneri, Staphylococcus aureus, and Bacillus subtilis).
The antitumor potential was evaluated in terms of activity against brine shrimp eggs and DNA interaction.
The mixed ligand complexes have exhibited moderate antibacterial activity and promising antitumor potential.
American Psychological Association (APA)
Khan, Hizbullah& Daraz, Nek& Khan, Muhammad Nasim& Said, Muhammad& Akhtar, Nosheen& Badshah, Amin…[et al.]. 2014. Synthesis, Structural Characterization, and Evaluation of the Biological Properties of Heteroleptic Palladium(II) Complexes. Bioinorganic Chemistry and Applications،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1016083
Modern Language Association (MLA)
Khan, Hizbullah…[et al.]. Synthesis, Structural Characterization, and Evaluation of the Biological Properties of Heteroleptic Palladium(II) Complexes. Bioinorganic Chemistry and Applications No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1016083
American Medical Association (AMA)
Khan, Hizbullah& Daraz, Nek& Khan, Muhammad Nasim& Said, Muhammad& Akhtar, Nosheen& Badshah, Amin…[et al.]. Synthesis, Structural Characterization, and Evaluation of the Biological Properties of Heteroleptic Palladium(II) Complexes. Bioinorganic Chemistry and Applications. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1016083
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016083