Clinical Significance of Resistin Expression in Osteoarthritis: A Meta-Analysis
Joint Authors
Li, Xiao-Chuan
Tian, Feng
Wang, Fei
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-29
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The objective of this study was to conduct a systematic review of literature evaluating human resistin expression as a diagnostic factor in osteoarthritis development and to quantify the overall diagnostic effect.
Method.
Relevant studies were identified and evaluated for quality through multiple search strategies.
Studies analyzing resistin expression in the development of OA were eligible for inclusion.
Data from eligible studies were extracted and included into the meta-analysis using a random-effects model.
Results.
Four case-control studies consisting of a total of 375 OA patients and 214 controls as well as three sex-stratified analyses composed of 53 males and 104 females were incorporated into our meta-analysis.
Our results revealed that resistin levels were significantly higher in male OA subjects and OA patients overall.
Country-stratified analysis yielded significantly different estimates in resistin levels between male OA subjects and female OA subjects in the Canadian subgroup but not among the French and USA subgroups.
Based on the resistin levels in OA cases and controls, resistin levels were heightened in OA patients in the Dutch population.
Conclusion.
These results support the hypothesis that high expression of resistin represents a significant and reproducible marker of poor progression in OA patients, especially in males.
American Psychological Association (APA)
Li, Xiao-Chuan& Tian, Feng& Wang, Fei. 2014. Clinical Significance of Resistin Expression in Osteoarthritis: A Meta-Analysis. BioMed Research International،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1016149
Modern Language Association (MLA)
Li, Xiao-Chuan…[et al.]. Clinical Significance of Resistin Expression in Osteoarthritis: A Meta-Analysis. BioMed Research International No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1016149
American Medical Association (AMA)
Li, Xiao-Chuan& Tian, Feng& Wang, Fei. Clinical Significance of Resistin Expression in Osteoarthritis: A Meta-Analysis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1016149
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016149