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Comparative Hair Restorer Efficacy of Medicinal Herb on Nude (Foxn 1 nu ) Mice
Joint Authors
Begum, Shahnaz
Lee, Mi Ra
Gu, Li Juan
Hossain, Md. Jamil
Kim, Hyun Kyoung
Sung, Chang Keun
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Eclipta alba (L.) Hassk, Asiasarum sieboldii (Miq.) F.
Maek (Asiasari radix), and Panax ginseng C.
A.
Mey (red ginseng) are traditionally acclaimed for therapeutic properties of various human ailments.
Synergistic effect of each standardized plant extract was investigated for hair growth potential on nude mice, as these mutant mice genetically lack hair due to abnormal keratinization.
Dried plant samples were ground and extracted by methanol.
Topical application was performed on the back of nude mice daily up to completion of two hair growth generations.
The hair density and length of Eclipta alba treated mice were increased significantly P > 0.001 than control mice.
Hair growth area was also distinctly visible in Eclipta alba treated mice.
On the other hand, Asiasari radix and Panax ginseng treated mice developing hair loss were recognized from the abortive boundaries of hair coverage.
Histomorphometric observation of nude mice skin samples revealed an increase in number of hair follicles (HFs).
The presence of follicular keratinocytes was confirmed by BrdU labeling, S-phase cells in HFs.
Therefore, Eclipta alba extract and/or phytochemicals strongly displayed incomparability of hair growth promotion activity than others.
Thus, the standardized Eclipta alba extract can be used as an effective, alternative, and complementary treatment against hair loss.
American Psychological Association (APA)
Begum, Shahnaz& Lee, Mi Ra& Gu, Li Juan& Hossain, Md. Jamil& Kim, Hyun Kyoung& Sung, Chang Keun. 2014. Comparative Hair Restorer Efficacy of Medicinal Herb on Nude (Foxn 1 nu ) Mice. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1016223
Modern Language Association (MLA)
Begum, Shahnaz…[et al.]. Comparative Hair Restorer Efficacy of Medicinal Herb on Nude (Foxn 1 nu ) Mice. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1016223
American Medical Association (AMA)
Begum, Shahnaz& Lee, Mi Ra& Gu, Li Juan& Hossain, Md. Jamil& Kim, Hyun Kyoung& Sung, Chang Keun. Comparative Hair Restorer Efficacy of Medicinal Herb on Nude (Foxn 1 nu ) Mice. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1016223
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016223