Prognostic Histopathological and Molecular Markers on Prostate Cancer Needle-Biopsies: A Review

Abstract EN

Prostate cancer is diverse in clinical presentation, histopathological tumor growth patterns, and survival.

Therefore, individual assessment of a tumor’s aggressive potential is crucial for clinical decision-making in men with prostate cancer.

To date a large number of prognostic markers for prostate cancer have been described, most of them based on radical prostatectomy specimens.

However, in order to affect clinical decision-making, validation of respective markers in pretreatment diagnostic needle-biopsies is essential.

Here, we discuss established and promising histopathological and molecular parameters in diagnostic needle-biopsies.