Efficacy of Autologous Bone Marrow Concentrate for Knee Osteoarthritis with and without Adipose Graft
Joint Authors
Centeno, Christopher
Pitts, John
Al-Sayegh, Hasan
Freeman, Michael D.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
We investigated the use of autologous bone marrow concentrate (BMC) with and without an adipose graft, for treatment of knee osteoarthritis (OA).
Methods.
Treatment registry data for patients who underwent BMC procedures with and without an adipose graft were analyzed.
Pre- and posttreatment outcomes of interest included the lower extremity functional scale (LEFS), the numerical pain scale (NPS), and a subjective percentage improvement rating.
Multivariate analyses were performed to examine the effects of treatment type adjusting for potential confounding factors.
The frequency and type of adverse events (AE) were also examined.
Results.
840 procedures were performed, 616 without and 224 with adipose graft.
The mean LEFS score increased by 7.9 and 9.8 in the two groups (out of 80), respectively, and the mean NPS score decreased from 4 to 2.6 and from 4.3 to 3 in the two groups, respectively.
AE rates were 6% and 8.9% in the two groups, respectively.
Although pre- and posttreatment improvements were statistically significant, the differences between the groups were not.
Conclusion.
BMC injections for knee OA showed encouraging outcomes and a low rate of AEs.
Addition of an adipose graft to the BMC did not provide a detectible benefit over BMC alone.
American Psychological Association (APA)
Centeno, Christopher& Pitts, John& Al-Sayegh, Hasan& Freeman, Michael D.. 2014. Efficacy of Autologous Bone Marrow Concentrate for Knee Osteoarthritis with and without Adipose Graft. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1016253
Modern Language Association (MLA)
Centeno, Christopher…[et al.]. Efficacy of Autologous Bone Marrow Concentrate for Knee Osteoarthritis with and without Adipose Graft. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1016253
American Medical Association (AMA)
Centeno, Christopher& Pitts, John& Al-Sayegh, Hasan& Freeman, Michael D.. Efficacy of Autologous Bone Marrow Concentrate for Knee Osteoarthritis with and without Adipose Graft. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1016253
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016253