Interfractional Variations of Tumor Centroid Position and Tumor Regression during Stereotactic Body Radiotherapy for Lung Tumor
Joint Authors
Sun, Yanan
Lu, Yufei
Cheng, Siguo
Guo, Wei
Ye, Ke
Zhao, Huiyun
Zheng, Xiaoli
Li, Dingjie
Wang, Shujuan
Yang, Chengliang
Ge, Hong
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
To determine interfractional changes of lung tumor centroid position and tumor regression during stereotactic body radiation therapy (SBRT).
Methods and Materials.
34 patients were treated by SBRT in 4-5 fractions to a median dose of 50 Gy.
The CT scans acquired for verification were registered with simulation CT scans.
The gross target volume (GTV) was contoured on all verification CT scans and compared to the initial GTV in treatment plan system.
Results.
The mean ( ± standard deviation, SD) three-dimension vector shift was 5.2 ± 3.1 mm.
The mean ( ± SD ) interfractional variations of tumor centroid position were - 0 .
7 ± 4 .
5 mm in anterior-posterior (AP) direction, 0.2 ± 3.1 mm in superior-inferior (SI) direction, and 0 .
4 ± 2 .
4 mm in right-left (RL) direction.
Large interfractional variations ( ≥ 5 mm) were observed in 5 fractions (3.3%) in RL direction, 16 fractions (10.5%) in SI direction, and 36 fractions (23.5%) in AP direction.
Tumor volume did not decrease significantly during lung SBRT.
Conclusions.
Small but insignificant tumor volume regression was observed during lung SBRT.
While the mean interfractional variations of tumor centroid position were minimal in three directions, variations more than 5 mm account for approximately a third of all, indicating additional margin for PTV, especially in AP direction.
American Psychological Association (APA)
Sun, Yanan& Lu, Yufei& Cheng, Siguo& Guo, Wei& Ye, Ke& Zhao, Huiyun…[et al.]. 2014. Interfractional Variations of Tumor Centroid Position and Tumor Regression during Stereotactic Body Radiotherapy for Lung Tumor. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1016254
Modern Language Association (MLA)
Sun, Yanan…[et al.]. Interfractional Variations of Tumor Centroid Position and Tumor Regression during Stereotactic Body Radiotherapy for Lung Tumor. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1016254
American Medical Association (AMA)
Sun, Yanan& Lu, Yufei& Cheng, Siguo& Guo, Wei& Ye, Ke& Zhao, Huiyun…[et al.]. Interfractional Variations of Tumor Centroid Position and Tumor Regression during Stereotactic Body Radiotherapy for Lung Tumor. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1016254
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016254