The Potential of MicroRNAs in Personalized Medicine against Cancers
Joint Authors
Saumet, Anne
Mathelier, Anthony
Lecellier, Charles-Henri
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-27
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
MicroRNAs orchestrate the expression of the genome and impact many, if not all, cellular processes.
Their deregulation is thus often causative of human malignancies, including cancers.
Numerous studies have implicated microRNAs in the different steps of tumorigenesis including initiation, progression, metastasis, and resistance to chemo/radiotherapies.
Thus, microRNAs constitute appealing targets for novel anticancer therapeutic strategies aimed at restoring their expression or function.
As microRNAs are present in a variety of human cancer types, microRNA profiles can be used as tumor-specific signatures to detect various cancers (diagnosis), to predict their outcome (prognosis), and to monitor their treatment (theranosis).
In this review, we present the different aspects of microRNA biology that make them remarkable molecules in the emerging field of personalized medicine against cancers and provide several examples of their industrial exploitation.
American Psychological Association (APA)
Saumet, Anne& Mathelier, Anthony& Lecellier, Charles-Henri. 2014. The Potential of MicroRNAs in Personalized Medicine against Cancers. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1016422
Modern Language Association (MLA)
Saumet, Anne…[et al.]. The Potential of MicroRNAs in Personalized Medicine against Cancers. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1016422
American Medical Association (AMA)
Saumet, Anne& Mathelier, Anthony& Lecellier, Charles-Henri. The Potential of MicroRNAs in Personalized Medicine against Cancers. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1016422
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016422