The Role of 18F-FDG PETCT in Large-Vessel Vasculitis: Appropriateness of Current Classification Criteria?
Joint Authors
van Eck-Smit, Berthe L. F.
Bennink, R. J.
Balink, H.
Verberne, Hein J.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-14
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Patients with clinical suspicion of large-vessel vasculitis (LVV) may present with nonspecific signs and symptoms and increased inflammatory parameters and may remain without diagnosis after routine diagnostic procedures.
Both the nonspecificity of the radiopharmaceutical 18F-FDG and the synergy of integrating functional and anatomical images with PET/CT offer substantial benefit in the diagnostic work-up of patients with clinical suspicion for LVV.
A negative temporal artery biopsy, an ultrasonography without an arterial halo, or a MRI without aortic wall thickening or oedema do not exclude the presence of LVV and should therefore not exclude the use of 18F-FDG PET/CT when LVV is clinically suspected.
This overview further discusses the notion that there is substantial underdiagnosis of LVV.
Late diagnosis of LVV may lead to surgery or angioplasty in occlusive forms and is often accompanied by serious aortic complications and a fatal outcome.
In contrast to the American College of Rheumatology 1990 criteria for vasculitis, based on late LVV effects like arterial stenosis and/or occlusion, 18F-FDG PET/CT sheds new light on the classification of giant cell arteritis (GCA) and Takayasu arteritis (TA).
The combination of these observations makes the role of 18F-FDG PET/CT in the assessment of patients suspected for having LVV promising.
American Psychological Association (APA)
Balink, H.& Bennink, R. J.& van Eck-Smit, Berthe L. F.& Verberne, Hein J.. 2014. The Role of 18F-FDG PETCT in Large-Vessel Vasculitis: Appropriateness of Current Classification Criteria?. BioMed Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1016462
Modern Language Association (MLA)
Balink, H.…[et al.]. The Role of 18F-FDG PETCT in Large-Vessel Vasculitis: Appropriateness of Current Classification Criteria?. BioMed Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-1016462
American Medical Association (AMA)
Balink, H.& Bennink, R. J.& van Eck-Smit, Berthe L. F.& Verberne, Hein J.. The Role of 18F-FDG PETCT in Large-Vessel Vasculitis: Appropriateness of Current Classification Criteria?. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1016462
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016462