![](/images/graphics-bg.png)
Serum Fetuin-A Levels in Patients with Cardiovascular Disease: A Meta-Analysis
Joint Authors
Sun, Ze-Lin
Xie, Qi-Ying
Guo, Gong-Liang
Ma, Ke
Huang, Yuan-Yuan
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-16
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Fetuin-A (FA) suppresses arterial calcification, promotes insulin resistance, and appears to be elevated in patients with cardiovascular diseases (CVD), but the data is still inconsistent.
To clarify the correlation between serum FA levels and the presence and severity of CVDs, we performed this meta-analysis.
Method.
Potential relevant studies were identified covering the following databases: PubMed, Embase, Web of Science, Cochrane Library, CISCOM, CINAHL, Google Scholar, China BioMedicine (CBM), and China National Knowledge Infrastructure (CNKI) databases.
Data from eligible studies were extracted and included in the meta-analysis using a random-effects model.
Results.
Ten case-control studies, including 1,281 patients with CVDs and 2,663 healthy controls, were included.
The results showed significant differences in serum levels of FA between the CVDs patients and the healthy controls (SMD = 1.36, 95%CI: 0.37–2.36, P=0.007).
Ethnicity-subgroup analysis implied that low serum FA levels are related to CVDs in Caucasians (SMD = 1.73, 95%CI: 0.20–3.26, P=0.026), but not in Asians (SMD = 1.04, 95%CI: −0.33–2.40, P=0.138).
Conclusion.
The data indicated that decreased serum FA level is correlated with the development of CVDs.
FA might be clinically valuable for reflecting the progression of CVDs.
American Psychological Association (APA)
Sun, Ze-Lin& Xie, Qi-Ying& Guo, Gong-Liang& Ma, Ke& Huang, Yuan-Yuan. 2014. Serum Fetuin-A Levels in Patients with Cardiovascular Disease: A Meta-Analysis. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1016475
Modern Language Association (MLA)
Sun, Ze-Lin…[et al.]. Serum Fetuin-A Levels in Patients with Cardiovascular Disease: A Meta-Analysis. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1016475
American Medical Association (AMA)
Sun, Ze-Lin& Xie, Qi-Ying& Guo, Gong-Liang& Ma, Ke& Huang, Yuan-Yuan. Serum Fetuin-A Levels in Patients with Cardiovascular Disease: A Meta-Analysis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1016475
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016475