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Arthroscopic Fixation of Cell Free Polymer-Based Cartilage Implants with a Bioinspired Polymer Surface on the Hip Joint: A Cadaveric Pilot Study
Joint Authors
Lahner, Matthias
Duif, Christian
Ficklscherer, Andreas
Kaps, Christian
Kalwa, Lukas
Seidl, Tobias
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-27
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
This study investigates the adhesion capacity of a polyglycolic acid- (PGA-) hyaluronan scaffold with a structural modification based on a planar polymer (PM) surface in a cadaver cartilage defect model.
Two cadaver specimens were used to serially test multiple chondral matrices.
In a cadaver hip model, cell free polymer-based cartilage implants with a planar bioinspired PM surface (PGA-PM-scaffolds) were implanted arthroscopically on 10 mm × 15 mm full-thickness femoral hip cartilage lesions.
Unprocessed cartilage implants without a bioinspired PM surface were used as control group.
The cartilage implants were fixed without and with the use of fibrin glue on femoral hip cartilage defects.
After 50 movement cycles and removal of the distraction, a rearthroscopy was performed to assess the outline attachment and integrity of the scaffold.
The fixation techniques without and with fibrin fixation showed marginal differences for outline attachment, area coverage, scaffold integrity, and endpoint fixation after 50 cycles.
The PGA-PM-scaffolds with fibrin fixation achieved a higher score in terms of the attachment, integrity, and endpoint fixation than the PGA-scaffold on the cartilage defect.
Relating to the outline attachment, area coverage, scaffold integrity, and endpoint fixation, the fixation with PGA-PM-scaffolds accomplished significantly better results compared to the PGA-scaffolds ( P = 0.03752 , P = 0.03078 , P = 0.00512 , P = 0.00512 ) .
PGA-PM-scaffolds demonstrate increased observed initial fixation strength in cadaver femoral head defects relative to PGA-scaffold, particularly when fibrin glue is used for fixation.
American Psychological Association (APA)
Lahner, Matthias& Duif, Christian& Ficklscherer, Andreas& Kaps, Christian& Kalwa, Lukas& Seidl, Tobias. 2014. Arthroscopic Fixation of Cell Free Polymer-Based Cartilage Implants with a Bioinspired Polymer Surface on the Hip Joint: A Cadaveric Pilot Study. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1016517
Modern Language Association (MLA)
Lahner, Matthias…[et al.]. Arthroscopic Fixation of Cell Free Polymer-Based Cartilage Implants with a Bioinspired Polymer Surface on the Hip Joint: A Cadaveric Pilot Study. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1016517
American Medical Association (AMA)
Lahner, Matthias& Duif, Christian& Ficklscherer, Andreas& Kaps, Christian& Kalwa, Lukas& Seidl, Tobias. Arthroscopic Fixation of Cell Free Polymer-Based Cartilage Implants with a Bioinspired Polymer Surface on the Hip Joint: A Cadaveric Pilot Study. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1016517
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016517