Novel RNA Markers in Prostate Cancer: Functional Considerations and Clinical Translation
Joint Authors
Pickl, Julia M. A.
Heckmann, Doreen
Ratz, Leonie
Klauck, Sabine M.
Sültmann, Holger
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-27
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The availability of ultra-high throughput DNA and RNA sequencing technologies in recent years has led to the identification of numerous novel transcripts, whose functions are unknown as yet.
Evidence is accumulating that many of these molecules are deregulated in diseases, including prostate cancer, and potentially represent novel targets for diagnosis and therapy.
In particular, functional genomic analysis of microRNA (miRNA) and long noncoding RNA (lncRNA) in cancer is likely to contribute insights into tumor development.
Here, we compile recent efforts to catalog differential expression of miRNA and lncRNA in prostate cancer and to understand RNA function in tumor progression.
We further highlight technologies for molecular characterization of noncoding RNAs and provide an overview of current activities to exploit them for the diagnosis and therapy of this complex tumor.
American Psychological Association (APA)
Pickl, Julia M. A.& Heckmann, Doreen& Ratz, Leonie& Klauck, Sabine M.& Sültmann, Holger. 2014. Novel RNA Markers in Prostate Cancer: Functional Considerations and Clinical Translation. BioMed Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1016548
Modern Language Association (MLA)
Pickl, Julia M. A.…[et al.]. Novel RNA Markers in Prostate Cancer: Functional Considerations and Clinical Translation. BioMed Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-1016548
American Medical Association (AMA)
Pickl, Julia M. A.& Heckmann, Doreen& Ratz, Leonie& Klauck, Sabine M.& Sültmann, Holger. Novel RNA Markers in Prostate Cancer: Functional Considerations and Clinical Translation. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1016548
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016548