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Effects of Soft Denture Liners on L929 Fibroblasts, HaCaT Keratinocytes, and RAW 264.7 Macrophages
Joint Authors
De Souza Costa, Carlos Alberto
MacHado, A. L.
Vergani, C. E.
Chaves, Carolina de Andrade Lima
Chaves de Souza, Pedro Paulo
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-11
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
The effects of six soft liners (Ufi Gel P (UG), Sofreliner S (SR), Durabase Soft (D), Trusoft (T), Coe Comfort (CC), and Softone (ST)) on L929, HaCat, and RAW 264.7 cells were investigated.
Eluates (24 and 48 h) from the materials were applied on the cells and the viability, type of cell death, and morphology were evaluated.
Cells were also seeded on the specimens’ surfaces (direct contact) and incubated (24 or 48 h), and viability was analyzed.
Controls were cells in culture medium without eluates or specimens.
For cell viability, no significant differences were found among materials or between extraction periods, and the liners were noncytotoxic or slightly cytotoxic.
Morphology of RAW 264.7 cells was altered by the 24 h eluates from CC and D and the 48 h eluates from SR, CC, and D.
The 24 and 48 h eluates from all materials (except T) increased the percentages of L929 necrotic cells.
For direct contact tests, the lowest cytotoxicity was observed for UG and SR.
Although eluates did not reduce viability, morphology alterations and increase in necrosis were seen.
Moreover, in the direct contact, effects on viability were more pronounced, particularly for D, T, CC and ST.
Thus, the use of UG and SR might reduce the risk of adverse effects.
American Psychological Association (APA)
Chaves, Carolina de Andrade Lima& De Souza Costa, Carlos Alberto& Vergani, C. E.& Chaves de Souza, Pedro Paulo& MacHado, A. L.. 2014. Effects of Soft Denture Liners on L929 Fibroblasts, HaCaT Keratinocytes, and RAW 264.7 Macrophages. BioMed Research International،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1016596
Modern Language Association (MLA)
Chaves, Carolina de Andrade Lima…[et al.]. Effects of Soft Denture Liners on L929 Fibroblasts, HaCaT Keratinocytes, and RAW 264.7 Macrophages. BioMed Research International No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-1016596
American Medical Association (AMA)
Chaves, Carolina de Andrade Lima& De Souza Costa, Carlos Alberto& Vergani, C. E.& Chaves de Souza, Pedro Paulo& MacHado, A. L.. Effects of Soft Denture Liners on L929 Fibroblasts, HaCaT Keratinocytes, and RAW 264.7 Macrophages. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1016596
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016596