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Detection and Measurement of the Intracellular Calcium Variation in Follicular Cells
Joint Authors
Herrera-Navarro, Ana M.
Terol-Villalobos, Iván R.
Jiménez-Hernández, Hugo
Peregrina-Barreto, Hayde
Gonzalez-Barboza, José-Joel
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-16
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
This work presents a new method for measuring the variation of intracellular calcium in follicular cells.
The proposal consists in two stages: (i) the detection of the cell’s nuclei and (ii) the analysis of the fluorescence variations.
The first stage is performed via watershed modified transformation, where the process of labeling is controlled.
The detection process uses the contours of the cells as descriptors, where they are enhanced with a morphological filter that homogenizes the luminance variation of the image.
In the second stage, the fluorescence variations are modeled as an exponential decreasing function, where the fluorescence variations are highly correlated with the changes of intracellular free Ca2+.
Additionally, it is introduced a new morphological called medium reconstruction process, which helps to enhance the data for the modeling process.
This filter exploits the undermodeling and overmodeling properties of reconstruction operators, such that it preserves the structure of the original signal.
Finally, an experimental process shows evidence of the capabilities of the proposal.
American Psychological Association (APA)
Herrera-Navarro, Ana M.& Terol-Villalobos, Iván R.& Jiménez-Hernández, Hugo& Peregrina-Barreto, Hayde& Gonzalez-Barboza, José-Joel. 2014. Detection and Measurement of the Intracellular Calcium Variation in Follicular Cells. Computational and Mathematical Methods in Medicine،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1016819
Modern Language Association (MLA)
Herrera-Navarro, Ana M.…[et al.]. Detection and Measurement of the Intracellular Calcium Variation in Follicular Cells. Computational and Mathematical Methods in Medicine No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1016819
American Medical Association (AMA)
Herrera-Navarro, Ana M.& Terol-Villalobos, Iván R.& Jiménez-Hernández, Hugo& Peregrina-Barreto, Hayde& Gonzalez-Barboza, José-Joel. Detection and Measurement of the Intracellular Calcium Variation in Follicular Cells. Computational and Mathematical Methods in Medicine. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1016819
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016819