Altered Intrinsic Connectivity Networks in Frontal Lobe Epilepsy: A Resting-State fMRI Study
Joint Authors
Cao, Xinzhi
Qian, Zhiyu
Xu, Qiang
Shen, Junshu
Zhang, Zhiqiang
Lu, Guang Ming
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-25
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Examining the resting-state networks (RSNs) may help us to understand the neural mechanism of the frontal lobe epilepsy (FLE).
Resting-state functional MRI (fMRI) data were acquired from 46 patients with FLE (study group) and 46 age- and gender-matched healthy subjects (control group).
The independent component analysis (ICA) method was used to identify RSNs from each group.
Compared with the healthy subjects, decreased functional connectivity was observed in all the networks; however, in some areas of RSNs, functional connectivity was increased in patients with FLE.
The duration of epilepsy and the seizure frequency were used to analyze correlation with the regions of interest (ROIs) in the nine RSNs to determine their influence on FLE.
The functional network connectivity (FNC) was used to study the impact on the disturbance and reorganization of FLE.
The results of this study may offer new insight into the neuropathophysiological mechanisms of FLE.
American Psychological Association (APA)
Cao, Xinzhi& Qian, Zhiyu& Xu, Qiang& Shen, Junshu& Zhang, Zhiqiang& Lu, Guang Ming. 2014. Altered Intrinsic Connectivity Networks in Frontal Lobe Epilepsy: A Resting-State fMRI Study. Computational and Mathematical Methods in Medicine،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1016840
Modern Language Association (MLA)
Cao, Xinzhi…[et al.]. Altered Intrinsic Connectivity Networks in Frontal Lobe Epilepsy: A Resting-State fMRI Study. Computational and Mathematical Methods in Medicine No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1016840
American Medical Association (AMA)
Cao, Xinzhi& Qian, Zhiyu& Xu, Qiang& Shen, Junshu& Zhang, Zhiqiang& Lu, Guang Ming. Altered Intrinsic Connectivity Networks in Frontal Lobe Epilepsy: A Resting-State fMRI Study. Computational and Mathematical Methods in Medicine. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1016840
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016840