Paraneoplastic Dermatomyositis with Carcinoma Cervix: A Rare Clinical Association
Joint Authors
Kumar, Sumir
Mahajan, B. B.
Kaur, Sandeep
Singh, Amarbir
Source
Case Reports in Dermatological Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-17
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Dermatomyositis is an uncommon inflammatory myopathy associated with cutaneous manifestations.
It may also occur as paraneoplastic syndrome associated with various malignancies, most common of which being lung, breast, stomach, rectum, kidney, or testicular cancer.
A postmenopausal woman presented to us with generalized itching along with skin rash and proximal muscle weakness of 2 years’ duration.
Examination revealed heliotrope rash and mechanic hands and muscle power 2/5 in proximal muscle groups of both upper and lower limbs.
A clinical diagnosis of dermatomyositis was made which was supported by raised lactate dehydrogenase levels and skin biopsy findings.
Past history was significant for vaginal discharge and bleeding per vagina.
Further work-up revealed carcinoma cervix and she was referred to oncology department for further management.
Temporal relationship and improvement of muscle weakness with treatment of underlying neoplasm supported its paraneoplastic nature.
So, final diagnosis of keratinizing squamous cell carcinoma of cervix with paraneoplastic dermatomyositis was made.
A nationwide cohort study of 1,012 patients with dermatomyositis in Taiwan revealed only 3 patients with cervical cancer.
So this case is being reported for its rare association with carcinoma cervix and to highlight the need of detailed evaluation for underlying malignancies in patients with dermatomyositis.
American Psychological Association (APA)
Kumar, Sumir& Mahajan, B. B.& Kaur, Sandeep& Singh, Amarbir. 2014. Paraneoplastic Dermatomyositis with Carcinoma Cervix: A Rare Clinical Association. Case Reports in Dermatological Medicine،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-1016983
Modern Language Association (MLA)
Kumar, Sumir…[et al.]. Paraneoplastic Dermatomyositis with Carcinoma Cervix: A Rare Clinical Association. Case Reports in Dermatological Medicine No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-1016983
American Medical Association (AMA)
Kumar, Sumir& Mahajan, B. B.& Kaur, Sandeep& Singh, Amarbir. Paraneoplastic Dermatomyositis with Carcinoma Cervix: A Rare Clinical Association. Case Reports in Dermatological Medicine. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-1016983
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016983