Acquired Factor XI Inhibitor Presenting as Spontaneous Bilateral Subdural Hematoma in an Elderly Patient

Joint Authors

Vazzana, Natale
Scarti, Luca
Beltrame, Chiara
Picchi, Antonella
Taccetti, Gianni
Fortini, Alberto

Source

Case Reports in Hematology

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-11-06

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Diseases

Abstract EN

Development of autoantibodies against coagulation factors is an uncommon bleeding disorder associated with cancer, autoimmune conditions, pregnancy, or no apparent disease.

Spontaneous FVIII inhibitors are the most frequently encountered; those against FXI have been only anecdotally reported.

We report a case of acquired FXI inhibitor presenting as fatal intracranial spontaneous bleeding in an elderly patient with history of cancer and previous transfusions.

Few cases of acquired FXI inhibitor have been reported in association with connective tissue disease, cancer, or surgery.

Bleeding includes mucocutaneous bleeding, postsurgical hemorrhage, or life-threatening events.

Treatment consists of arresting the bleeding and inhibitor eradication.

High degree of suspicion is essential to promptly diagnose and treat this uncommon condition.

American Psychological Association (APA)

Vazzana, Natale& Scarti, Luca& Beltrame, Chiara& Picchi, Antonella& Taccetti, Gianni& Fortini, Alberto. 2014. Acquired Factor XI Inhibitor Presenting as Spontaneous Bilateral Subdural Hematoma in an Elderly Patient. Case Reports in Hematology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1017097

Modern Language Association (MLA)

Vazzana, Natale…[et al.]. Acquired Factor XI Inhibitor Presenting as Spontaneous Bilateral Subdural Hematoma in an Elderly Patient. Case Reports in Hematology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1017097

American Medical Association (AMA)

Vazzana, Natale& Scarti, Luca& Beltrame, Chiara& Picchi, Antonella& Taccetti, Gianni& Fortini, Alberto. Acquired Factor XI Inhibitor Presenting as Spontaneous Bilateral Subdural Hematoma in an Elderly Patient. Case Reports in Hematology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1017097

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1017097