Autoimmune Demyelinating Polyneuropathy as a Manifestation of Chronic Graft-versus-Host Disease after Adult Cord Blood Transplantation in a Patient with Chronic Lymphocytic Leukemia
Joint Authors
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-14
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Immune mediated demyelinating disease after allogeneic stem cell transplantation is a rare entity with unclear etiology.
Acute inflammatory demyelinating polyneuropathy (AIDP) has been reported after related and adult unrelated allogeneic stem cell transplantation but no such case has been reported after unrelated cord blood transplantation.
We hereby present the first case of AIDP after double umbilical cord blood transplantation (DUCBT).
A 55-year-old man with chronic lymphocytic leukemia (CLL) received a cord blood transplant for relapsed refractory disease with high risk cytogenetics.
On day 221, patient presented with skin rash, tingling in both lower extremites, and ascending paralysis that progressed rapidly over the course of 2 days.
The workup resulted in a diagnosis of AIDP and administration of intravenous immunoglobulins plus steroids was initiated.
Motor and sensory powers were fully recovered and his chronic GVHD was managed for several months with single agent sirolimus.
American Psychological Association (APA)
Hogan, Fredrick& Solh, Melhem. 2014. Autoimmune Demyelinating Polyneuropathy as a Manifestation of Chronic Graft-versus-Host Disease after Adult Cord Blood Transplantation in a Patient with Chronic Lymphocytic Leukemia. Case Reports in Hematology،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-1017105
Modern Language Association (MLA)
Hogan, Fredrick& Solh, Melhem. Autoimmune Demyelinating Polyneuropathy as a Manifestation of Chronic Graft-versus-Host Disease after Adult Cord Blood Transplantation in a Patient with Chronic Lymphocytic Leukemia. Case Reports in Hematology No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-1017105
American Medical Association (AMA)
Hogan, Fredrick& Solh, Melhem. Autoimmune Demyelinating Polyneuropathy as a Manifestation of Chronic Graft-versus-Host Disease after Adult Cord Blood Transplantation in a Patient with Chronic Lymphocytic Leukemia. Case Reports in Hematology. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-1017105
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1017105