The Possible Efficacy of Artichoke in Fluconazole Related Hepatotoxicity
Joint Authors
Kurt, Hüseyin
Toprak, Omer
Bülbül, Erdoğan
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-03
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Although fluconazole related hepatotoxicity (FRH) is rare, mortal acute hepatic necrosis and jaundice were reported in immunocompromised states such as acquired immunodeficiency syndrome (AIDS) and bone marrow transplant (BMT).
We present a case of a patient with multiple sclerosis who developed hepatotoxicity with the use of a single 150 mg fluconazole tablet for fungal vaginitis, 10 days after methylprednisolone pulse treatment.
Our patient’s alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels were decreased, 1200 U/L and 800 U/L, respectively, and bilirubin levels were consistent at 37 mg/dL.
Artichoke which has anticholestatic and antioxidant properties was used by our patient.
She consumed a 30 mg artichoke leaf extract tea 3 times a day.
The bilirubin levels significantly declined at the end of the first week and all liver function tests were normalized within 2 months.
American Psychological Association (APA)
Kurt, Hüseyin& Toprak, Omer& Bülbül, Erdoğan. 2014. The Possible Efficacy of Artichoke in Fluconazole Related Hepatotoxicity. Case Reports in Hepatology،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-1017116
Modern Language Association (MLA)
Kurt, Hüseyin…[et al.]. The Possible Efficacy of Artichoke in Fluconazole Related Hepatotoxicity. Case Reports in Hepatology No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-1017116
American Medical Association (AMA)
Kurt, Hüseyin& Toprak, Omer& Bülbül, Erdoğan. The Possible Efficacy of Artichoke in Fluconazole Related Hepatotoxicity. Case Reports in Hepatology. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-1017116
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1017116