Amiodarone-Induced Thyrotoxic Thyroiditis: A Diagnostic and Therapeutic Challenge

Joint Authors

Barvalia, Umang
Amlani, Barkha
Pathak, Ram

Source

Case Reports in Medicine

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-11-12

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Medicine

Abstract EN

Amiodarone is an iodine-based, potent antiarrhythmic drug bearing a structural resemblance to thyroxine (T4).

It is known to produce thyroid abnormalities ranging from abnormal thyroid function testing to overt hypothyroidism or hyperthyroidism.

These adverse effects may occur in patients with or without preexisting thyroid disease.

Amiodarone-induced thyrotoxicosis (AIT) is a clinically recognized condition commonly due to iodine-induced excessive synthesis of thyroid, also known as type 1 AIT.

In rare instances, AIT is caused by amiodarone-induced inflammation of thyroid tissue, resulting in release of preformed thyroid hormones and a hyperthyroid state, known as type 2 AIT.

Distinguishing between the two states is important, as both conditions have different treatment implications; however, a mixed presentation is not uncommon, posing diagnostic and treatment challenges.

We describe a case of a patient with amiodarone-induced type 2 hyperthyroidism and review the current literature on the best practices for diagnostic and treatment approaches.

American Psychological Association (APA)

Barvalia, Umang& Amlani, Barkha& Pathak, Ram. 2014. Amiodarone-Induced Thyrotoxic Thyroiditis: A Diagnostic and Therapeutic Challenge. Case Reports in Medicine،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1017163

Modern Language Association (MLA)

Barvalia, Umang…[et al.]. Amiodarone-Induced Thyrotoxic Thyroiditis: A Diagnostic and Therapeutic Challenge. Case Reports in Medicine No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1017163

American Medical Association (AMA)

Barvalia, Umang& Amlani, Barkha& Pathak, Ram. Amiodarone-Induced Thyrotoxic Thyroiditis: A Diagnostic and Therapeutic Challenge. Case Reports in Medicine. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1017163

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1017163