![](/images/graphics-bg.png)
A Challenging Case of an Ectopic Cushing Syndrome
Joint Authors
Bettencourt, P.
Menezes Nunes, Joana
Pinho, Elika
Camões, Isabel
Maciel, João
Cabral Bastos, Pedro
Souto de Moura, Conceição
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-09
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Bronchopulmonary carcinoids are rare pulmonary neoplasms although they account for most cases of ectopic ACTH syndromes.
When feasible, the mainstay treatment is surgical resection of the tumor.
We report the case of a 52-year-old woman with signs and symptoms suggestive of hypercortisolism for 12 months, admitted to our department because of community acquired pneumonia.
Blood hormone analysis showed increased levels of ACTH and urinary free cortisol and nonsuppressibility to high- and low-dose dexamethasone tests.
Pituitary MRI showed no lesion and no central-to-peripheral ACTH gradient was present in bilateral inferior petrosal sinus sampling.
CRH stimulation test suggested an ectopic ACTH source.
Thoracic CT scan revealed a nodular region measuring 12 mm located in the inferior lingular lobule of the left superior lung with negative uptake by 18-FDG-PET scan and negative SRS.
The patient was successfully treated with an atypical lung resection and histology revealed an atypical bronchial carcinoid tumor with positive ACTH immunoreactivity.
This was an interesting case because the patient was admitted due to pneumonia that may have been associated with her untreated and chronic hypercortisolism and a challenging case of ectopic ACTH syndrome due to conflicting results on the diagnostic exams.
American Psychological Association (APA)
Menezes Nunes, Joana& Pinho, Elika& Camões, Isabel& Maciel, João& Cabral Bastos, Pedro& Souto de Moura, Conceição…[et al.]. 2014. A Challenging Case of an Ectopic Cushing Syndrome. Case Reports in Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1017207
Modern Language Association (MLA)
Menezes Nunes, Joana…[et al.]. A Challenging Case of an Ectopic Cushing Syndrome. Case Reports in Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1017207
American Medical Association (AMA)
Menezes Nunes, Joana& Pinho, Elika& Camões, Isabel& Maciel, João& Cabral Bastos, Pedro& Souto de Moura, Conceição…[et al.]. A Challenging Case of an Ectopic Cushing Syndrome. Case Reports in Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1017207
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1017207