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Successfully Treated Calcific Uremic Arteriolopathy: Two Cases of a High Anion Gap Metabolic Acidosis with Intravenous Sodium Thiosulfate
Joint Authors
Rein, Joshua L.
Miyata, Kana N.
Dadzie, Kobena A.
Gruber, Steven J.
Sulica, Roxana
Winchester, James F.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Calcific uremic arteriolopathy (CUA) is a rare and potentially fatal disorder of calcification involving subcutaneous small vessels and fat in patients with renal insufficiency.
We describe the successful use of intravenous sodium thiosulfate (STS) for the treatment of CUA in two patients.
The first case was complicated by the development of a severe anion gap metabolic acidosis, which was accompanied by a seizure.
Both patients had complete wound healing within five months.
Although STS should be considered in the treatment of CUA, little is known about pharmacokinetics and additional studies are required to determine dosing strategies to minimize severe potential side effects.
American Psychological Association (APA)
Rein, Joshua L.& Miyata, Kana N.& Dadzie, Kobena A.& Gruber, Steven J.& Sulica, Roxana& Winchester, James F.. 2014. Successfully Treated Calcific Uremic Arteriolopathy: Two Cases of a High Anion Gap Metabolic Acidosis with Intravenous Sodium Thiosulfate. Case Reports in Nephrology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1017277
Modern Language Association (MLA)
Rein, Joshua L.…[et al.]. Successfully Treated Calcific Uremic Arteriolopathy: Two Cases of a High Anion Gap Metabolic Acidosis with Intravenous Sodium Thiosulfate. Case Reports in Nephrology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1017277
American Medical Association (AMA)
Rein, Joshua L.& Miyata, Kana N.& Dadzie, Kobena A.& Gruber, Steven J.& Sulica, Roxana& Winchester, James F.. Successfully Treated Calcific Uremic Arteriolopathy: Two Cases of a High Anion Gap Metabolic Acidosis with Intravenous Sodium Thiosulfate. Case Reports in Nephrology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1017277
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1017277