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Malignant Peripheral Nerve Sheath Tumors of the Head and Neck: A Case Series and Literature Review
Joint Authors
Mullins, Brandon T.
Hackman, Trevor
Source
Case Reports in Otolaryngology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-11
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Malignant peripheral nerve sheath tumors (MPNSTs) of the head and neck are rare aggressive neoplasms with a poor prognosis.
This study describes the management and outcomes of 3 of our patients with MPNSTs of the head and neck.
Methods.
We identified 3 patients presenting with MPNST of the head and neck and treated at the University of North Carolina.
We compared our results to the literature from 1963 to 2014.
Results.
Mean follow-up was 31 months.
Average age at diagnosis was 44.7 years of age.
All patients received wide-local excision and adjuvant radiotherapy.
No patients recurred during the series.
Recurrence-free survival time for the patients was 45, 37, and 3 months, respectively.
Conclusions.
Our data series confirms that a combined-modality approach with complete surgical resection and adjuvant radiotherapy leads to improved outcomes in MPNSTs of the head and neck.
Nonetheless, due to historically poor outcomes, continued research into newer therapies needs to be explored.
American Psychological Association (APA)
Mullins, Brandon T.& Hackman, Trevor. 2014. Malignant Peripheral Nerve Sheath Tumors of the Head and Neck: A Case Series and Literature Review. Case Reports in Otolaryngology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1017498
Modern Language Association (MLA)
Mullins, Brandon T.& Hackman, Trevor. Malignant Peripheral Nerve Sheath Tumors of the Head and Neck: A Case Series and Literature Review. Case Reports in Otolaryngology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1017498
American Medical Association (AMA)
Mullins, Brandon T.& Hackman, Trevor. Malignant Peripheral Nerve Sheath Tumors of the Head and Neck: A Case Series and Literature Review. Case Reports in Otolaryngology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1017498
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1017498