Pulmonary Hemosiderosis in Children with Bronchopulmonary Dysplasia
Joint Authors
Kurahara, David
Morie, Marina
Yamane, Maya
Lam, Sarah
Matthews, Wallace
Yee, Keolamau
Yamamoto, Kara
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-17
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We describe a possible association between pulmonary hemosiderosis (PH) and a history of bronchopulmonary dysplasia (BPD).
Both patients were born at 28-week gestation and presented with PH at ages 22 months and 6 years, respectively.
Both initially presented with cough and tachypnea, and bronchoalveolar lavage showed evidence of hemosiderin-laden macrophages.
Initial hemoglobin levels were < 4 g/dL and chest radiographs showed diffuse infiltrates that cleared dramatically within days after initiation of intravenous corticosteroids.
In the first case, frank pulmonary blood was observed upon initial intubation, prompting the need for high frequency ventilation, immediate corticosteroids, and antibiotics.
The mechanical ventilation wean was made possible by the addition of mycophenolate mofetil (MMF) and hydroxychloroquine.
Slow tapering off of medications was accomplished over 6 years.
These cases represent a possible correlation between prematurity-associated BPD and PH.
We present a review of the literature regarding this possible association.
In addition, MMF proved to be life-saving in one of the PH cases, as it has been in pulmonary hemorrhage related to systemic lupus erythematosus.
Further studies are warranted to investigate the possible association between PH and prematurity-related BPD, as well as the use of MMF in the treatment of PH.
American Psychological Association (APA)
Kurahara, David& Morie, Marina& Yamane, Maya& Lam, Sarah& Matthews, Wallace& Yee, Keolamau…[et al.]. 2014. Pulmonary Hemosiderosis in Children with Bronchopulmonary Dysplasia. Case Reports in Pediatrics،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-1017564
Modern Language Association (MLA)
Kurahara, David…[et al.]. Pulmonary Hemosiderosis in Children with Bronchopulmonary Dysplasia. Case Reports in Pediatrics No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-1017564
American Medical Association (AMA)
Kurahara, David& Morie, Marina& Yamane, Maya& Lam, Sarah& Matthews, Wallace& Yee, Keolamau…[et al.]. Pulmonary Hemosiderosis in Children with Bronchopulmonary Dysplasia. Case Reports in Pediatrics. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-1017564
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1017564