Effectiveness and Safety of Infliximab in Two Cases of Severe Chondrocalcinosis: Nine Years of Follow-Up
Joint Authors
Bruges-Armas, Jácome
Bettencourt, Bruno F.
Couto, Ana R.
Lima, Manuela
Rodrigues, Ana M.
Vastesaeger, Nathan
Brown, Matthew A.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
|Objectives.
To investigate the efficacy of infliximab in the treatment of severe calcium pyrophosphate deposition diseases (CPPD).
Methods.
Two patients with severe CPPD and diffuse idiopathic skeletal hyperostosis- (DISH-) like phenotype are described.
Both patients were resistant to therapy with nonsteroidal anti-inflammatory drugs (NSAIDs).
Both patients were treated with infliximab, a TNF-α receptor antagonist, for nine years.
Results.
Treatment with infliximab resulted in major clinical and laboratory improvements without relevant side effects.
Conclusions.
These results suggest that infliximab may be an effective treatment of severe CPDD.
American Psychological Association (APA)
Bruges-Armas, Jácome& Bettencourt, Bruno F.& Couto, Ana R.& Lima, Manuela& Rodrigues, Ana M.& Vastesaeger, Nathan…[et al.]. 2014. Effectiveness and Safety of Infliximab in Two Cases of Severe Chondrocalcinosis: Nine Years of Follow-Up. Case Reports in Rheumatology،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1017705
Modern Language Association (MLA)
Bruges-Armas, Jácome…[et al.]. Effectiveness and Safety of Infliximab in Two Cases of Severe Chondrocalcinosis: Nine Years of Follow-Up. Case Reports in Rheumatology No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1017705
American Medical Association (AMA)
Bruges-Armas, Jácome& Bettencourt, Bruno F.& Couto, Ana R.& Lima, Manuela& Rodrigues, Ana M.& Vastesaeger, Nathan…[et al.]. Effectiveness and Safety of Infliximab in Two Cases of Severe Chondrocalcinosis: Nine Years of Follow-Up. Case Reports in Rheumatology. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1017705
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1017705